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Have you been wondering where to stay in Little Italy, San Diego? We’ve got you covered!

If you’re planning a trip to the lively neighborhood of Little Italy in San Diego, you’re in for a treat.

We’ve handpicked 15 of our favorite places to stay just for you! We’ve done all the legwork, so you can focus on packing your bags for your next visit to San Diego.

So sit back, relax, and explore our top suggestions. Your perfect San Diego getaway is just a few scrolls away!

My Top 3 Picks On Where To Stay In Little Italy San Diego

#1 Top Pick
A mansion with a Tudor design and green bushes in front, a neat choice for where to stay in Little Italy San Diego.

⭐️⭐️⭐️⭐️⭐️

Tudor Mansion

✅ Posturepedic Beds

✅ Hot Tub

✅ Foosball Table

#2 Pick
A small backyard with grass and a cozy seating area, a nice home to stay in Little Italy San Diego.

Naturally Lit Home

✅ Spacious Inside

✅ Big Backyard

✅ 2 Parking Spots

#3 Pick
A rooftop pool at Carte Hotel surrounded by tall buildings, a cool place where to stay in Little Italy San Diego.

Carte Hotel

✅ Outdoor Pool

✅ Sauna + Hot Tub

✅ Fitness Center

15 Best Places To Stay In Little Italy San Diego

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Banker’s Hill  | ✅ Book it!

This stunning mansion in Little Italy is your perfect luxury getaway in San Diego. It’s in an unbeatable location, just a few minutes away from The Convention Center, Gaslamp Quarter, Balboa Park, and the San Diego Zoo.

Located high above the city, the mansion offers breathtaking views of the beautiful San Diego Bay. This mansion is styled in Tudor architecture and Modern Decor.

The property strikes a perfect balance between tranquility and luxurious comfort and sleeps up to 10 people across 4 bedrooms and an additional sofa bed. 

A spacious living room with a fireplace and cozy couches, a nice choice for where to stay in Little Italy San Diego.
Photo Credit: Expedia

The property features the most comfortable amenities from the plush Posturepedic Beds to the finest Egyptian cotton sheets for a restful night’s sleep.

Top Features Include

  • This mansion provides 3 off-street parking spots, each capable of accommodating even the largest SUVs, making parking in San Diego easier.
  • If you require more space or have extra guests, a separate Penthouse unit with a private entrance is available for booking, offering complete independence and privacy.
  • Catering to both families and professionals, the property features a Foosball table, a Mini Golf putting green, and a Poker table to keep you entertained.

“The home was clean as promised, offered tons of room, and was centrally located to Coronado, Old Towne, Little Italy, Gaslamp, La Jolla & Balboa Park. The check-in process and communication were perfect and we enjoyed the stay. We would gladly return.”

David N (see more reviews)

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2. This Naturally Lit Home with an Outdoor Patio

⭐️ RATING: 4.9/5 Stars | 📍 LOCATION: Little Italy | ✅ Book it!

This gorgeous luxury home is located in the middle of Little Italy! The 3-bedroom, 2-bathroom home is the perfect upscale lodging for your visit to the area.

It can accommodate up to 6 guests, in this recently restored historical house that has ample natural light and spacious interiors.

Inside, you’ll find a welcoming ambiance complemented by tasteful decor. Enjoy modern amenities including a smart TV, high-speed Wi-Fi, and a fully equipped kitchen. All essentials including linens, towels, shampoo, conditioner, and body wash are provided.

An open living room with a dining area in the back, making it a homey spot where to stay in Little Italy San Diego.
Photo Credit: Expedia

Because it’s situated in the center of Little Italy, you’ll have easy access to top restaurants, art galleries, and the renowned Farmer’s Market. Plus, the property comes with 2 parking spots behind a secure gate.

The master bedroom comes with a king bed and en-suite bathroom, while the other 2 bedrooms offer queen beds.

Top Features Include

  • Recently restored 3-bedroom, 2-bathroom home for up to 6 guests
  • Spacious indoor areas including kitchen and living room
  • Expansive deck and backyard with secure parking

“My coworkers and I were in town for a conference. This house was perfect for our stay…clean, cute, and well-updated. It’s also close to great food and transportation. The backyard is amazing for a morning cup of coffee.”

Paul B (see more reviews)

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3. Carte Hotel with Outdoor Swimming Pool + Sun Terrace

⭐️ RATING: 4/5 Stars | 📍 LOCATION: Downtown | ✅ Book it!

The mid to upscale Carte Hotel (Curio Collection By Hilton) is a perfect location – in the center of downtown San Diego. Whether you’re visiting the area for business or leisure, this property offers a comfortable and convenient stay.

The air-conditioned rooms feature modern amenities such as flat-screen TVs, coffee machines, and private bathrooms with complimentary toiletries. Some rooms even have fully equipped kitchens with dishwashers, perfect for longer stays.

Relax and unwind at the outdoor swimming pool or soak up the sun on the sun terrace. The property also has private parking available on site and friendly staff on hand at reception ensures your stay will be hassle-free.

A modern hotel room with a big comfy bed, a great place to stay in Little Italy San Diego with a window view of the harbor.
Photo Credit: Expedia

💡 Pro Tip: Allow flexibility to get the best rates. Prices here vary greatly depending on the type of room you book, and the dates which may put some people off. Booking.com will show you the price/night when you search for dates.

Top Features Include

  • Central location in San Diego with easy access to attractions
  • Variety of room sizes accommodating 1 to 4 guests
  • Indoor amenities include a fitness center, sauna, and hot tub

“Great room, top restaurant and bar with excellent food. Lovely lobby area with bar and restaurant and modern facilities with pool and gyms.”

David, UK (see more reviews)

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4. Homewood Suites – Free Breakfast, Pool & On-Site Restaurant

⭐️ RATING: 4/5 Stars | 📍 LOCATION: Downtown | ✅ Book it!

Located near Downtown San Diego and Bayside, Homewood Suites By Hilton is where comfort meets convenience in San Diego’s Little Italy! While we haven’t stayed at this Homewood Suites, I’ve stayed in Homewood Suites in the past with my family and we’ve never had a negative experience!

This mid to upscale property offers a range of suites to suit everyone’s needs. Rooms range from comfy King Studio Suites to spacious 2 Bedroom Suites, accommodating anywhere from 1 to 8 guests.

Each suite features HD televisions, along with a fully equipped kitchen including a microwave, stovetop, and dishwasher. The separate living area provides plenty of space to unwind after a day of exploring San Diego.

Both the on-site fitness center and the year-round-accessible outdoor swimming pool are popular with guests.

A hotel room with a large bed and ocean view through floor-to-ceiling windows, a perfect spot on where to stay in Little Italy San Diego.
Photo Credit: Expedia

💡 Pro Tip: Like the previous Hilton hotel we mentioned, prices fluctuate significantly based on the room type and booking dates. Booking.com will show you the price/night when you search for dates.

Top Features Include

  • Variety of suites with fully equipped kitchens and separate living areas
  • Year-round outdoor pool
  • Complimentary continental breakfast and on-site restaurant

“The breakfast was excellent, a lot of variety to choose from. The location is great. Close to many restaurants. The staff was exceptionally helpful and professional…This was our third visit to this location and we will keep returning to this property because of the hospitality of the staff.”

Kamran, USA (see more reviews)

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5. This Spanish-Style Home with Garden & 2 Free Parking Spots

⭐️ RATING: 4.8/ 5 Stars | 📍 LOCATION: Little Italy | ✅ Book it!

This charming Spanish-style home is an upscale property that offers a perfect blend of historic charm and modern amenities, providing a comfortable home for up to 6 guests.

The property features classically decorated interior with inviting decor, hardwood floors, and plenty of natural light. The spacious living area features a comfortable couch, armchairs, and a 50-inch Roku TV, while the adjoining den offers additional social space and a poker table for 6.

Prepare delicious meals in the modern kitchen, which comes with stained wood cabinetry, dual sinks, and a full suite of appliances.

A bright living room with a blue sofa and wooden floors in a Spanish home on where to stay in Little Italy San Diego.
Photo Credit: Expedia

Bedrooms come with hotel-quality linens. Plus there’s even a private balcony in the main bedroom.

Outside features plenty of space to socialize or relax. The large back patio with a garden and umbrella-shaded table, is perfect for al fresco dining or simply sitting back with a cold beverage.

A heads up – this rental does not include a washer or dryer.

Top Features Include

  • Historic Spanish-style home with 3 patios and a garden
  • Convenient off-street parking for 2 vehicles
  • Prime location within walking distance of upscale boutiques, eateries, and attractions

“This home was in the heart of Little Italy. It was a perfect place to stay and never have to drive to eat drink or explore the city. We would definitely stay again!”

Lisa.C (see more reviews)

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6. Hilton Garden Inn – Rooftop Pool, Spa, Spacious Fitness Center

⭐️ RATING: 4/5 Stars | 📍 LOCATION: Downtown Bayside | ✅ Book it!

Experience comfort and convenience at the Hilton Garden Inn. This mid to upscale property is a great option if you want to stay close to Bayside.

There are a range of rooms available perfect for couples or a family of 4 – from cozy King rooms suitable for up to 2 adults to spacious Queen Suites with 2 large double beds for up to 4 people.

Rooms are 100% non-smoking rooms and equipped with modern amenities. This includes a 42-inch flat-screen HDTV, a work station with convenient outlets, an ergonomic chair, and a microwave and mini-refrigerator.

An indoor pool area with palm trees and a view of the city, a relaxing spot for guests figuring out where to stay in Little Italy San Diego.
Photo Credit: Expedia

You can opt for a hearty breakfast onsite at Bayside Kitchen + Bar or head to The Pavilion Pantry, the onsite convenience mart, and choose from a selection of light meals, snacks, and beverages.

💡 Pro Tip: Similar to the earlier Hilton hotels we’ve discussed, prices vary greatly depending on the room type and dates of booking. Booking.com will show you the price/night when you search for dates.

Top Features Include

  • Rooftop pool and spa
  • Spacious fitness center to maintain your workout routine
  • Bayside Kitchen + Bar serves delicious breakfast and dinner daily

“The location of this hotel is fantastic, next to Little Italy (tons of restaurants in walking distance) and close to the sea. we also had a nice breakfast with very friendly staff at the restaurant.”

Reto, Switzerland (see more reviews)

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7. This Large Modern Loft With Local Mural – Outdoor Patio & Grill

⭐️ RATING: 4.8/5 Stars | 📍 LOCATION: Downtown | ✅ Book it!

This hidden gem in Little Italy offers a unique and upscale experience for first-time visitors to San Diego.

This modernized loft, located just steps away from the iconic Little Italy Sign, and has one of the most spacious accommodations on our list. It’s perfect for families, couples, or groups of friends.

Inside, guests will find 2 flat-screen TVs, a fully stocked kitchen, and a completely redone bathroom with a huge shower. There’s also a garage for parking.

A trendy loft living room with colorful sofas and a large wall art, a cool place where to stay in Little Italy San Diego.
Photo Credit: Expedia

What makes this accommodation so unique is that it was once the private residence of renowned architect Jonathan Segal. The design offers a blend of comfort and sophistication.

Although this property can sleep up to 12 guests, it does only have 1 bathroom which could be challenging for some groups. 

Top Features Include

  • Modern loft with 2 bedrooms and 1 bathroom, sleeping up to 12 guests
  • Brand new space with a unique conversion from a Yoga studio, featuring a large mural by a local artist
  • Outdoor patio with a grill and bathtub

“The space actually feels bigger than the pictures look. It was perfect for our busy weekend as it was packed with a graduation and celebration, brunch, college tour, and family visits. Coming home to the townhouse after each event was relaxing with such a fun vibe. All the natural light that comes in is beautiful and it was great being so close to so much. We would definitely stay here again.”

Monica C (see more reviews)

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8. This European-Styled Penthouse with Multi Jet Hot Tub

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Bayside | ✅ Book it!

This Zen Penthouse is an upscale accommodation offers a calm ambiance with outstanding views of the city skyline and bay, creating an unforgettable escape for up to 4 guests.

Set in a historical building with a London feel, the penthouse features a contemporary interior. The design includes exclusive Restoration Hardware decor elements and Italian Quartz countertops.

A luxurious bathroom with a freestanding tub and urban view, perfect for unwinding when deciding where to stay in Little Italy San Diego.
Photo Credit: Expedia

The king-size Tempur-Pedic is adorned with Egyptian cotton sheets, and the bathroom comes complete with a jetted bathtub. Add to this, the spacious living area, has a 55-inch LED TV with access to all your favorite apps and you have the setting for a perfect romantic weekend getaway.

A downside to this property is the amount of stairs which might be an issue for anyone with mobility issues. 

Top Features Include

  • Luxurious penthouse with a European feel and panoramic views
  • Multi-jet hot tub and spacious living area
  • Comfy bed with Temper-Pedic mattress +Egyptian cotton sheets

“Easy check-in, great parking, and very clean. We had such a wonderful time. It’s a lovely and safe neighborhood. The hot tub was a major bonus too. The house has everything you need. Also, the beds and linens are so comfortable too. Would highly recommend it. Thank you again for everything!”

Anne C (see more reviews)

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9. The Palms Zen Villa – Hot Tub, Mini Golf & Spanish Gardens

⭐️ RATING: 4.9/5 Stars | 📍 LOCATION: Gaslamp Quarter | ✅ Book it!

If you want to experience luxury and tranquility, then stay at The Palms Zen Villa. This upscale property offers a quiet escape with stunning amenities. It’s a great choice for a romantic weekend break.

Outside, unwind in the Generalife-inspired gardens or soak in the hot tub while listening to water fountain sounds.

An outdoor patio with a hot tub and tropical wall art, an inviting place to stay and relax in Little Italy San Diego.
Photo Credit: Expedia

This beautifully decorated villa features a blend of Restoration Hardware elements and designer pieces. The spacious living area has a 55-inch LED TV with access to over 300 channels.

The bedroom has a king-size luxury collection bed with Egyptian cotton sheets to ensure a restful night’s sleep.

Other great features of this property are the free high-speed Wi-Fi, a kitchenette, and a washer/dryer.

Top Features Include

  • Luxurious villa with European-inspired decor and designer furnishings
  • Outdoor oasis with Spanish gardens and a hot tub
  • Centrally located within walking distance of Little Italy, the Gaslamp Quarter, and the Convention Center

“I have stayed in multiple vacation rentals. This is by far the best yet. The property exceeded all expectations with regard to location, cleanliness, communication, and livability. We would definitely return and recommend it to anyone looking for a high-quality experience!”

William M (see more reviews)

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10. Best Western Plus Bayside Inn – Heated Pool, Hot Tub, Near Airport

⭐️ RATING: 4/5 Stars | 📍 LOCATION: Downtown | ✅ Book it!

If you’re after comfort and convenience, Best Western Plus Bayside Inn is a great option, located just under 2 miles from San Diego International Airport. This midscale property offers a range of amenities for a pleasant stay.

Each room at Best Western Plus Bayside Inn is equipped with modern amenities including a cable TV with extended movie channels, microwave, refrigerator, and coffee machine. Safety deposit boxes are also provided for extra security.

A hotel room with a comfy bed and a balcony view of the bay, a great option for where to stay in Little Italy San Diego.
Photo Credit: Expedia

Rooms vary from the King Room, which is perfect for 2 guests, to the Queen Room with a Balcony and bay views for up to 4 guests.

They offer a complimentary grab-and-go breakfast which will set you up perfectly before heading out to explore Gaslamp Quarter and Little Italy districts – both just a short distance away.

After exploring Little Italy, relax in the heated outdoor pool or hot tub, or work out in the onsite fitness center which features state-of-the-art equipment.

The friendly staff and convenient amenities ensure a comfortable stay at Best Western Plus Bayside Inn.

Top Features Include

  • Spacious guest rooms featuring balconies with skyline views of San Diego
  • Complimentary grab-and-go breakfast served daily
  • Heated outdoor pool, hot tub, and fitness center

“Room was comfortable and with a good view of the bay. Close to Little Italy and bayside activities. Cheap parking for the car.”

Amelia, UK (see more reviews)

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11. Dutra Inn

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Bayfront

The Dutra Inn is a unique small hotel with 5 rooms, built with recycled materials. Each of the rooms is different in terms of size and decor and with different price ranges.

A modern loft with an open floor plan, comfy furniture, and industrial vibes, an awesome choice for where to stay in Little Italy San Diego.
Photo Credit: Expedia (Room D)

Room D – 1 bathroom, sleeps 2,700 sq. ft. Due to large windows and street-level location, potential for light and noise at night. The lofted bedroom is accessible via a steep ladder. The room has a utilitarian look with ancient train station doors 20 feet high. It’s bright and airy with accents of colorful furniture.

Room U – 1 bed, 1 bath, 2,700 sq. ft. Room U is accessible via 3 flights of outdoor stairs. Street-facing windows and patio may lead to light & noise at night. This room is bright and airy, finished with oriental-style antique furniture.

Room T – 1 bathroom, sleeps 2,300 sq. ft. Room T is accessed via 4 narrow outdoor flights of stairs. The bed is lofted, requiring the use of provided steps for access. This room has a Scandinavian feel with its white walls, exposed wood, and indoor plants. It features soft furnishings with South American patterns.

Room R – 1 bedroom, 1 bathroom, sleeps 2,500 sq. ft. The room is bright and airy with statement furniture and natural-toned soft furnishings. There are 2 sets of stairs inside, and large street-facing windows may cause light and noise at night. 

A bright living room with a colorful Southwestern-style throw and large windows, a welcoming spot for staying in Little Italy San Diego.
Photo Credit: Expedia (Room A)

Room A – 1 bathroom, sleeps 2,500 sq. ft. Located up 5 narrow flights of stairs with 3 sides of windows, providing light and potential noise at night. The room is bright and airy with plenty of South American accents, from the rugs to cushions. It even has a giant cactus!

“My friend and I absolutely loved our stay at The Dutra. Not only was the check-in process easy, the room was very clean, and located just minutes from the water, the individuals who work for The Dutra were incredibly kind and accommodating to us. 10/10 recommend.”

Mary M

12. Doma Napoli – Historic Gem with Pool Table and 2 TVs

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Little Italy | ✅ Book it!

Introducing Doma Napoli, a historic gem located in the Little Italy neighborhood! This upscale property offers a charming and convenient stay in one of San Diego’s most sought-after areas.

Step inside this 900-square-foot unit and discover a cozy retreat with all the comforts of home. 

A fun game room with a pool table and sports memorabilia, part of a cool place to stay in Little Italy San Diego.
Photo Credit: Expedia

On the first floor of a 2-story house, this unit features 1 queen bed and 2 twin beds, accommodating up to 4 guests comfortably. The bathroom has a jetted bathtub.

Located just a block from Piazza della Famiglia, the heart of Little Italy, you’ll find yourself surrounded by charming cobblestone streets, bustling restaurants, and cafes. 

With a parking spot provided, although not required, everything is within walking distance from this house.

Top Features Include

  • Spacious 2-bedroom unit with a fully equipped kitchen
  • Assigned parking space for 1 vehicle
  • Enjoy amenities such as mini-split AC units, 2 TVs, washer and dryer, and a pool table

“Fantastic location! Very easy keypad entry to the apartment and extremely convenient parking. Would stay here again on a future visit to San Diego”

Darlene M (see more reviews)

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13. Well-Located Luxury Condo In Little Italy

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Little Italy| ✅ Book it!

This one-of-a-kind luxury condo is located right in the center of Little Italy. This 2-bedroom condo has an interior that’s stylishly decorated with open space, modern amenities, and plenty of room to relax.

Relax on the balcony or patio and soak. The property also has a fully equipped kitchen. 

The primary bedroom features a queen bed and a double futon, while the second bedroom offers another queen bed, ensuring a comfortable night’s sleep for everyone. There are also 2 bathrooms with bathtubs or showers. 

A cozy living area with a white couch and a large compass wall art, offering a relaxing stay in Little Italy San Diego.
Photo Credit: Expedia

It’s conveniently located near the trolley so you can easily explore popular destinations like the Gaslamp Quarter or Petco Park. 

An important consideration here is that children under 12 years old are not permitted to stay. 

Top Features Include

  • Well-equipped with a full kitchen, in-suite laundry, and parking
  • Great location with easy access to beaches, eateries, and entertainment
  • Sleeps up to 6 guests with 2 queen beds and a double futon, best for families or groups

“Here with family – Great restaurants, lots of choices to enjoy the wines and wonderful food. Farmers Market on Wednesdays and Saturdays. Great location to access everything. LOVE LOCATION!!!”

Lynn K (see more reviews)

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14. Stylish Downtown Loft with Free Onsite Parking

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Little Italy | ✅ Book it!

Experience the charm of downtown living at this stylish loft, perfect for a couple’s getaway to San Diego. With its super high ceilings, exposed brick, and large southern-facing window, the loft has an open and inviting atmosphere.

The loft features a comfortable double bed tucked away in the lofted area, accessed via a staircase/ladder. The bathroom and dressing area is spacious and well-appointed with all the essentials.

A chic living space with a long green couch, concrete walls, and a high ceiling, a stylish option for where to stay in Little Italy San Diego.
Photo Credit: Expedia

This property is only a short walk away from popular attractions like the Waterfront Park, and the USS Midway

You can enjoy exploring the area on foot and soaking in the local architecture and design, stopping off in the numerous shops, restaurants, and cafes to discover nearby. 

Another added bonus is the free onsite parking spot included.

It’s important to note that families with young children are not permitted in this property.

Top Features Include

  • Super high ceilings and large windows create a bright and airy space
  • Efficient kitchen with all the essentials for cooking at home
  • Pet-friendly with a grassy outdoor area and pet waste bags provided

We stayed two nights and it was the perfect size and location. Rachel was attentive and had great recommendations. Little Italy is fun, beautiful and very close to downtown and the water. Would stay here again!

Holly G (see more reviews)

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15. Porta D’ Italia – Top Floor Condo With Gym and Secure Parking

⭐️ RATING: 5/5 Stars | 📍 LOCATION: Port of San Diego | ✅ Book it!

Located in the port area of San Diego, this top-floor condo offers a prime location surrounded by amazing restaurants, cafes, and shops. Despite it being in a busy area, this corner unit is incredibly quiet, with well-insulated walls to ensure you have a peaceful stay.

The condo is equipped with everything you need. It features modern amenities like a multifunction printer/scanner/copier and a Bluetooth speaker – this makes it an ideal rental for digital nomads who prefer slow travel.

A rooftop terrace with patio furniture and city views, a great place to hang out while staying in Little Italy San Diego.
Photo Credit: Expedia

Other facilities here are the onsite gym as well as a common-area patio with plenty of seating and gas BBQ grills, perfect for relaxation and admiring the views of the sailboats on the bay.

The drawback with this accommodation is that it’s only available for month-long stays, so it’s not suitable for a short break to San Diego. 

Top Features Include

  • Prime location in Little Italy, close to restaurants, cafes, and shops
  • Quiet top-floor corner unit with well-insulated walls
  • Access to a beautifully appointed gym and a common area patio with bay views

Aron is the perfect landlord. He replies very fast and helps, if you have any questions. This apartment is in the 4th floor and has the best view of any apartments there. You see some skyscrapers and look in the atrium with the terrace on the 2nd floor… if you want to work, study or travel for al long time in San Diego, it’s very good place to live.

Diana R. (see more reviews)

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FAQs – Accommodations In Little Italy San Diego

What is the best part of San Diego to stay in?

Little Italy is considered one of the best neighborhoods to stay in San Diego. It offers a welcoming atmosphere with an abundance of dining options, lively bars and cafes, and quaint boutiques to explore.

Is Little Italy considered downtown?

Yes, Little Italy is a neighborhood located in downtown San Diego. It is bordered by San Diego Bay to the west and Interstate 5 to the east.

Is Little Italy a good place to live in San Diego?

Yes, Little Italy is a highly desirable neighborhood to live in San Diego. It has a strong sense of community and offers a mix of urban living with a small-town feel.

Is Little Italy safe?

Yes, Little Italy is considered a safe neighborhood by day and by night.  It has a lower crime rate compared to other areas in San Diego. 

🤩 If you’re looking for a lux mansion, then check out this modern mansion.

Final Thoughts: Where to Stay In Little Italy San Diego

If you’re planning a trip to the vibrant neighborhood of Little Italy in San Diego, consider making your stay as unforgettable as the city itself.

Whether you’re planning a romantic weekend getaway or a larger gathering with friends and family, there are so many great places to stay in Little Italy to suit every style of travel.

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